Potential fungicidal and bactericidal agents. Synthesis of certain 4- (2-amino-1,3,4-thiadiazol-5-yl) quinolines
El-Dine, S.A.; El-Khawass, S.M.
Die Pharmazie 34(9): 537-538
1979
ISSN/ISBN: 0031-7144 PMID: 542485 Document Number: 153881
The synthesis of some new 4-[2-alkyl (aryl or aralkyl) amino-1,3,4-thiadiazol-5-yl]-2-substituted quinolines is described. IR, UV, NMR and MS data of representative examples are discussed. Most of the compounds prepared showed a reasonable antifungal and antimicrobial activity.
Document emailed within 1 workday
Related Documents
Abdel-Mohsen, S.A.; Hussein, E.M. 2014: A green synthetic approach to the synthesis of Schiff bases from 4-amino-2-thioxo-1,3-diazaspiro[5.5]undec-4-ene-5-carbonitrile as potential anti-inflammatory agents Bioorganicheskaia Khimiia 40(3): 370-376Moron, J.; Rautureau, M.; Huel, C.; Pierré, A.; Berthier, L.K.; Atassi, G.; Bisagni, E. 1993: Synthesis and evaluation of 4-amino-substituted 7-methoxy (and 7-hydroxy)- 11-methyl (and 5,11-dimethyl)-10H-pyrido [2,3-b] carbazoles and 4-amino- substituted 11-methyl (and 5,11-dimethyl)-10H-pyrido[3',4':4,5] pyrrolo [3,2-g] quinolines, two new series related to antitumor ellipticine derivatives Anti-Cancer Drug Design 8(6): 399-416
Singh, A.K.; Lohani, M.; Singh, U.P. 2011: Synthesis, characterization and biological activity of some 1, 3, 4-thiadiazol derivatives Pakistan Journal of Pharmaceutical Sciences 24(4): 571-574
Pérez de Salazar, J.L.; Díaz Loya, F.J.; García Mendoza, M. 1983: The trichomonacidal, fungicidal and bactericidal effects of metacresol sulfonic acid polymer with methanal in cervico-vaginitis Ginecologia y Obstetricia de Mexico 51(310): 43-48
Kwapiszewski, W.; Borkowski, L. 1987: Amino acid derivatives of 2-(p-chlorophenoxy)-2-methylpropionic acid as compounds with potential antilipemic agents. II. Preparation of methyl esters of N-[2-(p-chlorophenoxy)-2-methylpropionyl] amino acids Acta Poloniae Pharmaceutica 44(2): 121-131
Böttcher, M.; Henklein, P.; Hoffmann, K.; Heder, G.; Siems, W.E.; Niedrich, H. 1986: Synthesis of n-substituted amino acid-p-nitrobenzyl esters as potential ACE inhibitors Die Pharmazie 41(2): 140
Shoeb, H.A.; Koekor, M.I. 1979: Synthesis and biological activity evaluation of some quinolines Research Communications in Chemical Pathology and Pharmacology 23(2): 359-365
Hazzaa, A.A.; Ashour, F.; Shafik, R.M. 1980: Synthesis of 1,2,4-triazolythiopropanolamines as potential cardiovascular agents Die Pharmazie 34(5-6): 324-325
Librowski, T.; Czarnecki, R.; Jastrzebska, M. 1999: Chiral 2-amino-1-butanol xanthone derivatives as potential antiarrhythmic and hypotensive agents Acta Poloniae Pharmaceutica 56(1): 87-90
Chawla, R.; Arora, A.; Parameswaran, M.K.; Chan, P.; Sharma, D.; Michael, S.; Ravi, T.K. 2010: Synthesis of novel 1,3,4-oxadiazole derivatives as potential antimicrobial agents Acta Poloniae Pharmaceutica 67(3): 247-253
Habib, N.S.; Abdel-Hamid, S.; el-Hawash, M. 1989: Synthesis of benzimidazole derivatives as potential antimicrobial agents Farmaco 44(12): 1225-1232
Ryczek, J.; Kusowska, J. 1983: Synthesis of 3-dialkylaminopropyl-2-thiohydant derivatives as potential antiarrhythmic agents Il Farmaco; Edizione Scientifica 38(6): 383-390
Shafik, R.M.; Ibrahim, E.A.; el-Khawass, E.M.; el-Hawash, S.A.; el-Dardiry, S.A. 1989: Synthesis of some 2-(3,4-dimethoxy-phenyl)-1,3-propanediamines as potential dopaminergic agents Die Pharmazie 44(2): 115-118
Farghaly, A.M.; Mohsen, A.; Omar, M.E.; Khalil, M.A.; Gaber, M.A. 1990: Synthesis of 3-aryl-2-substituted-4(3H)-quinazolines as potential antimicrobial agents Farmaco 45(4): 431-438
Rykowski, A.; Pucko, W. 1999: Synthesis of 5-imino-5H-dipyrido[1,2-a; 2',3'-d]pyrimidines as potential antiallergy agents (1) Acta Poloniae Pharmaceutica 56(1): 57-60
Bernáth, G.; Fülöp, F.; Kóbor, J. 1993: Syntheses of potential drugs from 1-[bis(hydroxymethyl)methyl]-6,7-dialkoxy-1,2,3,4-tetrahydrois o- quinolines Acta Pharmaceutica Hungarica 63(3): 129-137
Wagner, G.; Vieweg, H.; Leistner, S. 1993: Synthesis of 11-aryl-7,8,9,10-tetrahydro-1,2,3-triazino-(4',5':4,5)-thienol- -(2,3-b)-quinolines with antianaphylactic action Die Pharmazie 48(8): 576-578
Yoshimura, Y.; Watanabe, M.; Sakata, S.; Ashida, N.; Miyazaki, S.; Machida, H.; Matsuda, A. 1995: A facile synthesis of 4'-thio-arabinonucleosides as potential antiviral agents from D-glucose Nucleic Acids Symposium Series 34: 21-22
Rida, S.M.; Salama, H.M.; Labouta, I.M.; A-Ghany, Y.S. 1985: Synthesis of some 3-(benzimidazol-2-ylmethyl)thiazolidinone derivatives as potential antimicrobial agents Die Pharmazie 40(10): 727-728
Wu, K.M.; Zhang, M.Y.; Fang, Z.; Huang, L. 1985: Potential antileukemic agents, synthesis of derivatives of indirubin, indigo, and isoindigotin Yao Xue Xue Bao 20(11): 821-826